Presinusoidal Portal Hypertension

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Updated: May 02, 2022

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1

What is Presinusoidal?

[pre″si-nŭ-soi´d'l] located in front of a sinusoid or affecting the circulation before the sinusoids are reached; used especially to denote the location of vascular resistance in portal hypertension.
2

What causes Prehepatic portal hypertension?

Prehepatic causes include splenic vein thrombosis and portal vein thrombosis. These conditions commonly are associated with hypercoagulable states and with malignancy (eg, pancreatic cancer).
3

How does schistosomiasis cause portal hypertension?

The classic form of presinusoidal portal hypertension is caused by the deposition of Schistosoma oocytes in presinusoidal portal venules, with the subsequent development of granulomata and portal fibrosis. Schistosomiasis is the most common noncirrhotic cause of variceal bleeding worldwide.
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2. Cancertherapyadvisor.com

Portal hypertension - Cancer Therapy Advisor

https://www.cancertherapyadvisor.com/home/decision-support-in-medicine...

Portal hypertension is defined as a pathologic elevation in portal venous pressures. The causes are classified as presinusoidal, sinusoidal, or postsinusoidal.

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