Carvedilol In Portal Hypertension

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Updated: April 29, 2022

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1

Can carvedilol be used for portal hypertension?

Carvedilol is a promising agent, and seems to be more effective than propranolol in hemodynamic studies. The efficacy in primary prevention of variceal bleeding suggests that carvedilol has a role in the management of clinically significant portal hypertension.
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Is carvedilol better than propranolol in portal hypertension?

Therefore carvedilol has been shown to be superior to propranolol in causing of acute, long-term and overall reduction of the hepatic venous pressure gradient, i.e., portal venous pressure. The proportion of patients who demonstrated an adequate response is also higher for carvedilol.
3

Which beta-blocker is best for portal hypertension?

Propranolol is a noncardioselective beta-blocker that reduces portal pressure through the reduction of portal and collateral blood flow.
4

Is carvedilol good for liver disease?

In this study, we have shown that carvedilol therapy in these patients was associated with reduced risk of mortality, particularly in those with mild ascites. We concluded that low dose, chronic treatment with carvedilol in patients with liver cirrhosis and ascites is not detrimental.
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www.wiley.com. John Wiley & Sons, Inc., commonly known as Wiley (/ˈwaɪli/), is an American multinational publishing company founded in 1807 that focuses on academic publishing and instructional materials.
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2. Bmj.com

Carvedilol for portal hypertension in cirrhosis - BMJ Open

https://bmjopen.bmj.com/content/6/5/e010902

Carvedilol is an emerging therapy for portal hypertension. On the basis of its mechanism of action by α and β receptors blockade, it might have a more ...

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