Saag Portal Hypertension

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Updated: May 18, 2022

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Mdcalc.com

FAQs

1

Why is SAAG high in portal hypertension?

The increase in hydrostatic pressure causes more fluid to leave the circulation into the peritoneal space (ascites). The SAAG subsequently increases because there is more free fluid leaving the circulation, concentrating the serum albumin.
2

What does a SAAG score mean?

SAAG = serum albumin – ascites albumin. A high gradient (SAAG >1.1 g/dL) indicates portal hypertension and suggests a nonperitoneal cause of ascites. Such conditions may include the following: Cirrhosis. Fulminant hepatic failure.
3

Why is SAAG high in heart failure?

Cardiac ascites can also complicate right-sided congestive heart failure. Many such patients have a high serum ascites albumin gradient (SAAG) with high ascites protein content as a consequence of the high systemic venous pressures of the liver and peritoneal cavity (see Chapter 91).
4

What is the SAAG in SBP?

One of the first measures to calculate from the ascitic fluid analysis is the serum-to-ascites albumin gradient (SAAG). The SAAG is measured by subtracting the serum albumin level from the ascites fluid albumin level.
2. Sciencedirect.com

Serum-Ascites Albumin Gradient - an overview - Science Direct

https://www.sciencedirect.com/topics/medicine-and-dentistry/serum-asci...

The SAAG is based on oncotic-hydrostatic balance. Portal hypertension results in an abnormally high hydrostatic pressure gradient between the portal bed and ...

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