Portal Hypertension Pathophysiology

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Updated: June 29, 2022

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Nih.gov

FAQs

1

What is portal hypertension and why does it occur in cirrhosis?

Portal hypertension is a leading side effect of cirrhosis. Your body carries blood to your liver through a large blood vessel called the portal vein. Cirrhosis slows your blood flow and puts stress on the portal vein. This causes high blood pressure known as portal hypertension.
2

What are the 3 categories of portal hypertension?

With regard to the liver itself, causes of portal hypertension usually are classified as prehepatic, intrahepatic, and posthepatic.
3

Why does portal hypertension cause systemic vasodilation?

An increase in splanchnic blood flow in portal hypertension is the result of a marked vasodilation of arterioles in splanchnic organs, which drain blood into the portal venous system[35].
2. Merckmanuals.com

Portal Hypertension - Hepatic and Biliary Disorders - Merck ...

https://www.merckmanuals.com/en-ca/professional/hepatic-and-biliary-di...

Portal hypertension is often associated with a hyperdynamic circulation. Mechanisms are complex and seem to involve altered sympathetic tone, production of ...

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