Portal Systemic Encephalopathy Index

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Updated: April 30, 2022

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Nih.gov

FAQs

1

What are the grades of encephalopathy?

Grade 2: lethargy or apathy, minimal disorientation for time or place, subtle personality change, inappropriate behaviour, impaired performance of subtraction. Grade 3: somnolence to semi stupor but responsive to verbal stimuli, confusion, gross disorientation. Grade 4: coma (unresponsive to verbal or noxious stimuli).
2

What lab value indicates hepatic encephalopathy?

The ammonia level can help diagnose encephalopathy although its ability is less clear in chronic liver disease. Ammonia levels over 123 are likely to improve with lactulose therapy. An ammonia level more than 200 strongly suggests hepatic encephalopathy.
3

How is encephalopathy measured?

Minimal hepatic encephalopathy is detected through psychometric testing (eg, the number connection test, the digit symbol test, the block design test, reaction times to light or sound, and the reaction time to interference in a task). Minimal hepatic encephalopathy is most likely the result of hyperammonemia.
4

How many grades are there in hepatic encephalopathy?

The most often used is the West Haven criteria (WHC), which differentiate between four grades of clinically overt HE.
2. Oup.com

Current concepts in the assessment and treatment of Hepatic ...

https://academic.oup.com/qjmed/article/103/1/9/1539314

Calculation of the portal-systemic encephalopathy (PSE) score and index may also objectively describe ...

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