Portal Cirrhosis Pathology

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Updated: June 09, 2022

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Nih.gov

FAQs

1

What is the pathology of cirrhosis of the liver?

Cirrhosis is a late stage of scarring (fibrosis) of the liver caused by many forms of liver diseases and conditions, such as hepatitis and chronic alcoholism. Each time your liver is injured — whether by disease, excessive alcohol consumption or another cause — it tries to repair itself.
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What is the pathophysiology of portal hypertension?

Portal hypertension is characterized by a pathologic increase in portal venous pressure that leads to the formation of an extensive network of portosystemic collaterals that divert a large fraction of portal blood to the systemic circulation, bypassing the liver.
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What are the key histologic features of cirrhosis?

Histologically, cirrhosis is characterized by vascularized fibrotic septa that link portal tracts with each other and with central veins, leading to hepatocyte islands that are surrounded by fibrotic septa and which are devoid of a central vein (Figure 1).
2. Pathologyoutlines.com

Cirrhosis - Pathology Outlines

https://www.pathologyoutlines.com/topic/livercirrhosis.html

Cirrhosis · Diffuse disruption in architecture of the entire liver (loss of normal central - portal relationship) · Bridging fibrous septa ...

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