Depmap Portal

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Updated: May 13, 2022

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Broadinstitute.org

The Eli and Edythe L. Broad Institute of MIT and Harvard, often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States.

(617) 714-7000 Merkin Building, 415 Main St, Cambridge, MA 02142

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1

What is the DepMap portal?

Welcome to the DepMap Portal!
The goal of the Dependency Map (DepMap) portal is to empower the research community to make discoveries related to cancer vulnerabilities by providing open access to key cancer dependencies analytical and visualization tools.
2

What is CCLE dataset?

The CCLE provides public access to genomic data, visualization and analysis for over 1100 cancer cell lines. This dataset contains RNA-Seq Aligned Reads, WXS Aligned Reads, and WGS Aligned Reads data.
3

What is the cancer dependency map?

The Cancer Dependency Map integrates the work of multiple experimental and computational research project at the Sanger Institute with the shared aim of identifying dependencies in cancer cells which could be exploited to develop new therapies.
4

Is Broad Institute legit?

The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and it partners with the Massachusetts Institute of Technology, Harvard University, and the five Harvard teaching hospitals.
5

What is Broad Institute famous for?

The Eli and Edythe L. Broad Institute of MIT and Harvard is a globally renowned genomics institute that has created a pioneering model of biomedical science.
6

Is Broad Institute part of MIT?

The Broad Institute of MIT and Harvard is a research organization that convenes a community of researchers from across many disciplines and partner institutions—MIT, Harvard, and Harvard-affiliated hospitals.
2. Elifesciences.org

ShinyDepMap, a tool to identify targetable cancer ... - eLife

https://elifesciences.org/articles/57116

The Cancer Dependency Map (DepMap) is an ongoing project to identify essential genes across hundreds of cancer cell lines using genome-wide ...

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