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Updated: April 24, 2022
Thus, nonselective beta blockers are effective at most stages of cirrhosis, from the patient with clinically significant portal hypertension who has no or small ...
By slowing the heart rate and widening the blood vessels, beta-blocker medicines such as propranolol and nadolol appear to lower the blood pressure in varices that bypass the liver. In people who have esophageal varices, beta-blockers have been shown to reduce the risk of having a first episode of bleeding.
Consequently, they reduce portal pressure. In primary prophylaxis, beta blockers reduced the bleeding risk from 30 to 15%; in secondary prophylaxis, this risk ...
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